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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
18.48
Human Site:
Y186
Identified Species:
25.42
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
Y186
D
V
W
M
V
E
F
Y
A
P
W
C
G
H
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
Y270
D
V
W
M
V
E
F
Y
A
P
W
C
G
H
C
Dog
Lupus familis
XP_532876
440
48280
Y186
D
V
W
M
V
E
F
Y
A
P
W
C
G
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
Y186
D
V
W
M
V
E
F
Y
A
P
W
C
G
H
C
Rat
Rattus norvegicus
Q63081
440
48155
Y186
D
V
W
M
V
E
F
Y
A
P
W
C
G
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
V182
W
A
A
A
A
T
E
V
K
D
Q
T
K
G
K
Chicken
Gallus gallus
Q8JG64
505
56163
S186
N
Y
R
F
A
H
T
S
E
E
Q
L
V
Q
K
Frog
Xenopus laevis
NP_001086643
442
47765
E186
S
D
D
V
W
L
V
E
F
F
A
P
W
C
G
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
F186
D
V
W
L
V
E
F
F
A
P
W
C
G
H
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K226
E
L
N
E
E
N
L
K
K
F
A
Q
V
Q
S
Honey Bee
Apis mellifera
XP_395981
427
47177
C182
Y
A
P
W
C
G
H
C
K
N
L
A
P
I
W
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
W185
V
L
N
S
K
D
I
W
L
V
E
F
F
A
P
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
E174
E
L
T
D
G
N
F
E
K
E
V
L
N
S
K
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
A179
A
P
E
W
T
K
A
A
N
N
L
Q
G
K
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
L136
E
G
G
T
N
V
K
L
A
A
V
P
Q
N
V
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
N92
V
N
C
D
L
N
K
N
K
A
L
C
A
K
Y
Red Bread Mold
Neurospora crassa
Q92249
369
39263
V143
K
G
S
A
P
S
L
V
N
I
L
N
D
A
T
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
0
0
86.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
6.6
6.6
100
N.A.
13.3
0
20
20
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
13.3
N.A.
N.A.
20
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
6
12
12
0
6
6
42
12
12
6
6
12
0
% A
% Cys:
0
0
6
0
6
0
0
6
0
0
0
42
0
6
36
% C
% Asp:
36
6
6
12
0
6
0
0
0
6
0
0
6
0
0
% D
% Glu:
18
0
6
6
6
36
6
12
6
12
6
0
0
0
0
% E
% Phe:
0
0
0
6
0
0
42
6
6
12
0
6
6
0
0
% F
% Gly:
0
12
6
0
6
6
0
0
0
0
0
0
42
6
6
% G
% His:
0
0
0
0
0
6
6
0
0
0
0
0
0
36
0
% H
% Ile:
0
0
0
0
0
0
6
0
0
6
0
0
0
6
0
% I
% Lys:
6
0
0
0
6
6
12
6
30
0
0
0
6
12
18
% K
% Leu:
0
18
0
6
6
6
12
6
6
0
24
12
0
0
0
% L
% Met:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
12
0
6
18
0
6
12
12
0
6
6
6
0
% N
% Pro:
0
6
6
0
6
0
0
0
0
36
0
12
6
0
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
12
6
12
0
% Q
% Arg:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
0
6
6
0
6
0
6
0
0
0
0
0
6
6
% S
% Thr:
0
0
6
6
6
6
6
0
0
0
0
6
0
0
6
% T
% Val:
12
36
0
6
36
6
6
12
0
6
12
0
12
0
12
% V
% Trp:
6
0
36
12
6
0
0
6
0
0
36
0
6
0
6
% W
% Tyr:
6
6
0
0
0
0
0
30
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _